GastroPanel

REF: 601 040.02

GastroPanel® is a first line diagnostic test for dyspeptic patients. It is a non-invasive blood test, risk free and user friendly laboratory test.

GastroPanel gives information on the structure and function of the stomach mucosa, and of the risks caused by a possible abnormal mucosa.


GastroPanel gives information on the structure and function of the stomach mucosa, and of the risks caused by a possible abnormal mucosa. Based on the GastroPanel results, it is possible to get information to support the diagnosis of:

  • Healthy stomach mucosa
  • Functional and organic dyspepsia (when GastroPanel results indicate a healthy stomach mucosa, the cause of stomach problems is often functional dyspepsia or a disease outside the stomach).
  • Atrophic gastritis (damaged stomach mucosa that is severly dysfunctional) and likelihoods of the conditions specifically in the corpus and antrum areas of the stomach (normal, gastritis or atrophic gastritis).
  • Helicobacter pylori infection.
  • Achlorhydria of the stomach (anacidic stomach).

 

The test panel consists of four assays:

  • Pepsinogen I ELISA
  • Pepsinogen II ELISA
  • Gastrin-17 ELISA
  • Helicobacter pylori IgG ELISA

For more information about the GastroPanel, please visit www.gastropanel.com

Instructions

Reference

1.AgréusL,KuipersEJ,KupcinskasL,MalfertheinerP,DiMarioF,LejaM,MahachaiV, YaronN,vanOijenM,PerezPerezG,RuggeM,RonkainenJ,SalaspuroM,Sipponen P,SuganoK,SungJ.Rationaleindiagnosisandscreeningofatrophicgastritiswith stomachspecificplasmabiomarkers.ScandJGastroenterol2012;47:136-147.

2.   BenberinV,BektayevaR,KarabayevaR,LebedevA,AkemeyevaK,Paloheimo L,SyrjänenK.PrevalenceofH.pyloriInfectionandAtrophicGastritisAmong

Symptomatic and Dyspeptic Adults in Kazakhstan. A Hospital based Screening StudyUsingaPanelofSerumBiomarkers.AnticancerReresearch2013;33:4595- 4602.

3.   Germana B, Di Mario F, Cavallaro LG, Moussa AM, Lecis P, Liatoupolou S,Comparato G,CarloniC,BertiatoG,BattiestelB,PapaN,AragonaG,CavestroGM,IoriV,MerliR, BertoliniS,CaruanaP,FranzeA.ClinicalusefulnessofserumpepsinogensIandII, gastrin-17andanti-Helicobacterpyloriantibodiesinthemanagementofdyspeptic patientsinprimarycare.DigLiverDis2005;37:501–508.

4.   SipponenP,HärkönenM.Hypochlorhydricstomach:ariskconditionforcalcium malabsorptionandosteoporosis?ScandJGastroenterol2010;45:133-138.

5.   Storskrubb T, Aro P, Ronkainen J, Sipponen P, Nyhlin H, Talley NJ, Engstrand L, Stolte M, Vieth M, Walker M, Agreus L. Serum biomarkers provide an accurate methodfordiagnosisofatrophicgastritisinageneralpopulation:TheKalixanda study.ScandJGastroenterol2008;43:1448-1455.

6.   Telaranta-KeerieA,KaraR,PaloheimoL,HärkönenM,SipponenP.Prevalenceof undiagnosedadvancedatrophiccorpusgastritisinFinland:anobservationalstudy among4256volunteerswithoutspecificcomplaints.ScandJGastroenterol2010; 45:1036-1041.

7.   VäänänenH,VauhkonenM,HelskeT,KääriäinenI,RasmussenM,Tunturi-Hihnala H, Koskenpato J, Sotka M, Turunen M, Sandström R, Ristikankare M, Jussila A, Sipponen P. Non-Endoscopic Diagnosis of Atrophic Gastritis with a Blood Test. Correlation between Gastric Histology and Serum Levels of Gastrin-17 and PepsinogenI.AMulticentreStudy.EurJGastroenterolHepatol2003;15:885-891.

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